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Gyne-Lotrimin 3 Combination Packan imidazole derivative with a broad spectrum of antimycotic activityinhibits biosynthesis of the sterol ergostolan important component of fungal cell membranesIts action leads to increased membrane permeability and apparent disruption of enzyme systems bound to the membraneBetamethasone and clotrimazole are used together to treat cutaneous tinea infectionsIn studies in fungal culturesthe minimum fungicidal concentration of clotrimazole caused leakage of intracellular phosphorous compounds into the ambient medium with concomitant breakdown of cellular nucleic acidsand accelerated potassium etfluxBoth of these events began rapidly and extensively after addition of the drug to the culturesThe primary action of clotrimazole is against dividing and growing organisms.

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As with many other topical antifungal drugstopical clotrimazole is not effective for onychomycosisThis condition usually requires treatment with an oralsystemicantifungal drug.

The termringwormorringwormsrefers to fungal infections that are on the surface of the skinA physical examination of.

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